Spanish Airports: http://www.aena.es
The commercial airports closest to Salamanca are Adolfo Suárez Madrid-Barajas and Valladolid-Villanubla. Adolfo Suárez Madrid-Barajas is the largest Spanish airport and there are regular flights from/to most national/ international destinations.

Bus: https://www.avanzabus.com/
There is a direct bus from Madrid airport to Salamanca. There are two bus stops to travel to Salamanca. The Avanzabus/AutoRes bus departs from the bus stop located in Terminal T1 of Madrid-Barajas airport (ground floor, opposite baggage reclaim hall 2):

And then it stops in the bus stop located in Terminal T4 of Madrid-Barajas airport (ground floor) before beginning the journey to Salamanca:

https://www.aena.es/en/adolfo-suarez-madrid-barajas/getting-there/bus.html#wcs-id-1575047995833

Alternatively, you can take the underground/a taxi to travel to the central bus station in Madrid (Estación de Autobuses de Madrid – Estación Sur) and take a bus from Madrid city centre to Salamanca. You can buy the bus ticket online in advance. The bus journey from Madrid to Salamanca takes approximately 2 hours and 40 minutes.

Train: http://www.renfe.com/EN/viajeros/index.html
The trains to Salamanca depart from Madrid-Chamartín train station. You can take the underground/a taxi/commuter rail service (Cercanías Madrid) to travel to Madrid-Chamartín train station from Madrid-Barajas airport. You can buy the train ticket online in advance. The train journey from Madrid to Salamanca takes approximately 2 hours and 30 minutes, although there are some faster trains at certain times that reach Salamanca in less than 2 hours.

Categoría de nivel principal o raíz: Cursos